Characters in a story have a goal. Conflict prevents them from achieving this goal. What happens now? That what readers want to know.
Man vs. Self: Mental Illness. Deciding between what is moral. Picking between two choices that that go against each other.
Man vs. Man: Very common. Most stories revolve around one person in a conflict with another. Hero vs. villain.
Man vs. Society: When a person goes against the law, policies, government, culture, tradition.
Man vs. Nature: Mother nature is raw and uncontrollable. This is fighting against the elements, flora and fauna, and surrounding
“Man vs. Supernatural: Higher powers, magic, or anything that cannot be rationally explained.